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Rhodopsin kinase GRK1 Antibodies
AND GRK1 ELISA kits, Rhodopsin kinase GRK1 Proteins
Many biological assays use antibodies to detect Rhodopsin kinase GRK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rhodopsin kinase GRK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rhodopsin kinase GRK1 antibodies...
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GRK1 Infographic by Boster Bio
All GRK1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1251
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1251
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2261
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2261
1 kit, containing two 96-well plates and all necessary reagents
GRK1 Overview
Facts about Rhodopsin kinase GRK1.
Rhodopsin kinase GRK1 (GRK1)
Retina-specific kinase involved in the sign turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is vital for scotopic vision and permits rapid adaptation to changes in illumination.
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Gene Information
| Human | |
|---|---|
| Gene Name: | GRK1 |
| Uniprot: | Q15835 |
| Entrez: | 6011 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
G protein-coupled receptor kinase 1rhodopsin kinase; GPRK1; GRK1; RHOK; RHOKEC 2.7.11; RKEC 2.7.11.14
Molecular Weight
Mass (kDA):
63.526 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q34 |
| Sequence: | 13; NC_000013.11 (113645771..113737736) |
Tissue Specificity
Retinal-specific. Expressed in rods and cones cells.
Subcellular Localizations
Membrane; Lipid-anchor. Cell projection, cilium, photoreceptor outer segment. Subcellular location is not affected by light or dark conditions.
Diseases
- Congenital Night Blindness
- Night Blindness
- Blind Vision
- Retinal Degeneration
- Retinitis Pigmentosa
- Congenital Stationary Night Blindness
- Retinal Diseases
- Malignant Neoplasms
- Neoplasms
- Dystrophy
- Photophobia
- Flasher - Visual Manifestation
Pathways
- Phototransduction
- Localization
- Transport
- Prenylation
- Cell Death
- Regeneration
- Cell Activation
- Photoreceptor Cell Differentiation
- Aging
- T Cell Activation
- Immune Response
- Pigmentation
- Reflex
PTMs
- Phosphorylation
- Prenylation
- Farnesylation
- Methylation
- Dephosphorylation
Research Areas
- Protein Kinase
- Signal Transduction
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRK1
bosterbio.com/bosterbio-gene-info-cards/GRK1
References
PMID: 9147475 by Zhao X., et al. Molecular cloning and localization of rhodopsin kinase in the mammalian pineal.
PMID: 8812493 by Khani S.C., et al. Characterization and chromosomal localization of the gene for human rhodopsin kinase.